purine analogue — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1038	Fludarabine	NSC 118218,Fludarabinum,F-ara-A	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , STAT
	Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and...
T1825	Reversine		Aurora Kinase , Adenosine Receptor , Autophagy
	Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).		Aurora Kinase , Adenosine Receptor , Autophagy
TNU0031	5-Hydroxyuridine	OHUrd	Nucleoside Antimetabolite/Analog
	5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.		Nucleoside Antimetabolite/Analog
T22231	Adenosine Dialdehyde (ADOX)	Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde	Others
	Adenosine Dialdehyde (Periodate-oxidized adenosine) is a purine nucleoside analogue. Adenosine Dialdehyde is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent...		Others
T2218	8-Azaguanine	Azaguanine-8,SK 1150,NSC-749,SF-337	Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
	8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.
TNU0130	2'-O-Methyl-2-thiouridine		Nucleoside Antimetabolite/Analog
	2'-O-Methyl-2-thiouridine is a purine nucleoside analogue present in synthetic thermophilic bacterial tRNAs. 2'-O-Methyl-2-thiouridine is more selective for A than unmodified U.		Nucleoside Antimetabolite/Analog
TNU0007	3'-Deoxy-3'-fluoroadenosine		Nucleoside Antimetabolite/Analog
	3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne encephalitis virus (TBEV), Zika virus and West Nile virus (WNV...		Nucleoside Antimetabolite/Analog
T75037	N1-Methoxymethyl pseudouridine
	N1-Methoxymethyl pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition o...
T75052	7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine
	7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms...
T71768	CB10-277
	CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alk...
T69099	Azathioprine Sodium
	Azathioprine Sodium is the sodium salt form of azathioprine, a pro-drug of purine analogue with immunosuppressive activity. Azathioprine is converted in vivo to its active metabolite 6-mercaptopurine (6-MP), which substi...
T75034	N1-Methylsulfonyl pseudouridine
	N1-Methylsulfonyl pseudouridine, a purine nucleoside analogue, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and...
T75036	N1-(2-Methyl)propyl pseudouridine
	N1-(2-Methyl)propyl pseudouridine, a purine nucleoside analogue, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include DNA synthesis inhibition and apop...
T75081	(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine
	(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine, a purine nucleoside analogue, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms including DNA synthesis inhibition and apoptosis...
T75033	Adenosine-2-carboxy methyl amide
	Adenosine-2-carboxy methyl amide, a purine nucleoside analogue, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms including DNA synthesis inhibition and apoptosis induction.[1]
T75087	Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
	Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester, a purine nucleoside analogue, demonstrates broad antitumor activity particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA...
T75038	N1-Benzoyl pseudouridine
	N1-Benzoyl pseudouridine, a purine nucleoside analogue, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and th...
T75077	2’-β-C-Methyl-3-deazauri dine
	2’-β-C-Methyl-3-deazauridine, a purine nucleoside analogue, exhibits wide antitumor activity specifically against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the ...
T75088	Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester
	Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester, a purine nucleoside analogue, exhibits broad antitumor activity, specifically targeting indolent lymphoid malignancies. Its anticancer mechanisms include t...
T75041	6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy, particularly against indolent lymphoid malignancies. Its anticancer mechanisms i...